Electrochemical Preparation of Synergistic Nanoantimicrobials

Molecules

Daniela Longano¹  Nicoletta Ditaranto¹  Luisa Torsi¹  MariaChiara Sportelli¹  Luigia Sabbatini¹  Nicola Cioffi¹  Giuseppina Tantillo²  Elisabetta Bonerba² 

[1] Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, via Orabona 4, I–70125 Bari, Italy;Dipartimento di Medicina Veterinaria, Università degli Studi di Bari Aldo Moro, Strada Prov. 62 per Casamassima, Km 3, I–70010 Valenzano (BA), Italy;

关键词: copper nanoparticle;    benzalkonium chloride;    synergistic antimicrobial;    nanomaterial;    xps;    tem;    etaas;   

DOI  :  10.3390/molecules25010049

来源: DOAJ

【 摘 要 】

The rapid spreading of resistance among common bacterial pathogens towards the misused antibiotics/disinfectant agents has drawn much attention worldwide to bacterial infections. In light of this, the present work aimed at the realization of core−shell nanoparticles possessing remarkable antimicrobial properties thanks to the synergistic action of the metal core and the disinfectant shell. Copper nanoparticles stabilized by benzalkonium chloride were prepared, characterized, and implemented in poly-vinyl-methyl ketone to obtain nanoantimicrobial composite coatings. Bioactivity tests are reported, proving the excellent disinfectant properties of the proposed nanomaterials, as compared to one of the well-known and strongest silver-based nanoantimicrobials. Applications are also briefly described.

【 授权许可】

Unknown