The safety of catheter ablation for premature ventricular contractions in patients without structural heart disease

BMC Cardiovascular Disorders

Ri-peng Yin¹  Yang-pei Peng¹  Jin-sheng Wang¹  Saroj Thapa¹  Yang-jing Xue¹  Yi-gen Shen¹  Jia-feng Lin¹  Kang-ting Ji¹  Lian-ming Liao² 

[1] Department of Cardiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University;Department of Laboratory Medicine, Union Hospital, Fujian Medical University;

关键词: Premature ventricular contractions;    Catheter ablation;    Structural heart diseases;   

DOI  :  10.1186/s12872-018-0913-2

来源: DOAJ

【 摘 要 】

Abstract Background Patients with frequent premature ventricular contractions (PVCs) are often symptomatic. Catheter ablation was usually indicated to eliminate symptoms in patients with PVCs-induced cardiomyopathy. Currently, PVCs-ablation is also applied for patients with PVCs and no structural heart diseases (SHD); however, the safety and efficacy of ablation in these patients remains unclear. Methods In this retrospective study, data from patients who underwent ablation for PVCs from January 2010 to December 2016 at our hospital was retrieved. Predictors of complications and acute procedural success were evaluated. Results A total of 1231 patients (mean age 47.8 ± 16.8 years, 59% female) were included. The overall complication rate was 2.7%, and the most common complication was hydropericardium. Two ablation-related mortalities occurred. One patient died of coronary artery injury during the procedure and the other died from infectious endocarditis. Location (left ventricle and epicardium) was the main predictor of complications, with right ventricular outflow tract (RVOT) predicting fewer complications. The acute procedural success rate was 94.1% in all patients. The main predictor of acute procedural success was RVOT origin, while an epicardial origin was a predictor of procedural failure. Conclusion Locations of left ventricle and epicardium were predictors of procedural complications for patients with PVCs. Therefore, ablation is not recommended in these patients. For other origins of PVCs, particularly RVOT origin, ablation is a safety and effective treatment.

【 授权许可】

Unknown