Polycystic ovary syndrome mouse model by prenatal exposure to high anti-Müllerian hormone

STAR Protocols

Paolo Giacobini¹  Nour El Houda Mimouni² 

[1] Cognition, UMR-S1172, 59000 Lille, France;;Univ. Lille, Inserm, CHU Lille, Laboratory of Development and Plasticity of the Postnatal Brain, Lille Neuroscience &

关键词: Health Sciences;    Metabolism;    Model Organisms;   

DOI  :  

来源: DOAJ

【 摘 要 】

Summary: Here, we describe a protocol that provides the steps required for the generation of a mouse model of polycystic ovary syndrome (PCOS) by exposing dams to elevated levels of anti-Müllerian hormone during late gestation. This protocol also describes the steps required to assess the PCOS-like equivalents of the Rotterdam PCOS diagnostic criteria in mice.For complete details on the use and execution of this protocol, please refer to Tata et al. (2018) and Mimouni et al. (2021).

【 授权许可】

Unknown