Bacterial infections in cirrhosis: Current treatment

Annals of Hepatology

Luis A. Ponce de León-Garduño¹  Jonathan Aguirre-Valadez²  Aldo Torre-Delgadillo³  Godolfino Miranda-Zazueta³ 

[1] Department of Infectious Diseases, Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán”, Mexico City, Mexico;Gastroenterology and Hepatology ABC Medical Center, Mexico City, Mexico;Hepatology and Liver Transplantation Unit, Department of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán”, Mexico City, Mexico;

关键词: Sepsis;    Multidrug-resistant;    Acute-on-chronic liver failure;    Liver;    Cirrhosis;   

DOI  :  

来源: DOAJ

【 摘 要 】

Bacterial infections frequently cause decompensating events in cirrhotic patients and are also the most common factor identified for the development of acute-on-chronic liver failure (ACLF). The increase in the prevalence of infections caused by multidrug-resistant (MDR) microorganisms has resulted in the reduced effectiveness of empiric antimicrobial treatment. We conducted a PubMed search from the last 20 years using the Keywords cirrhosis; multidrug-resistant; infections; diagnosis; treatment; prophylaxis; monitoring; sepsis; nutrition and antibiotic resistant. We made a review about bacterial infections among cirrhotic patients; we mainly focus on the description of diagnostic tools; biomarkers; clinical scores for diagnosis and prognosis also; we made an analysis concerning the monitoring of cirrhotic patients with sepsis and finally made some recommendations about the treatment; prophylaxis and prevention.

【 授权许可】

Unknown