Frontiers in Systems Neuroscience | |
Impact of appetitive and aversive outcomes on brain responses: Linking the animal and human literatures | |
Ronny N Gentry1  Luiz ePessoa1  Srikanth ePadmala1  Gregory B Bissonette1  Matthew R Roesch1  | |
[1] University of Maryland, College Park; | |
关键词: salience; reward processing; Neural Encoding; value encoding; appetitive and aversive outcomes; | |
DOI : 10.3389/fnsys.2014.00024 | |
来源: DOAJ |
【 摘 要 】
Decision-making is motivated by the possibility of obtaining reward and/or avoiding punishment. Though many have investigated behavior associated with appetitive or aversive outcomes, few have examined behaviors that rely on both. Fewer still have addressed questions related to how anticipated appetitive and aversive outcomes interact to alter neural signals related to expected value, motivation, and salience. Here we review recent rodent, monkey, and human research that address these issues.Further development of this area will be fundamental to understanding the etiology behind human psychiatric diseases and cultivating more effective treatments.
【 授权许可】
Unknown