Usefulness of Aerobic Exercise for Home Blood Pressure Control in Patients with Diabetes: Randomized Crossover Trial

Journal of Clinical Medicine

Kazufumi Okada¹  Isao Yokota¹  Hiroshi Okada²  Yoshitaka Hashimoto³  Masahide Hamaguchi³  Masahiro Yamazaki³  Takafumi Senmaru³  Keiko Iwai³  Saori Majima³  Emi Ushigome³  Michiaki Fukui³  Naoko Nakanishi³  Mai Asano³ 

[1] Department of Biostatistics, Graduate School of Medicine, Hokkaido University, Hokkaido 060-0808, Japan;Department of Endocrinology and Diabetology, Matsushita Memorial Hospital, Osaka 570-8540, Japan;Department of Endocrinology and Metabolism, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan;

关键词: home blood pressure;    randomized crossover trial;    hypertension;    type 2 diabetes;    aerobic exercise;   

DOI  :  10.3390/jcm11030650

来源: DOAJ

【 摘 要 】

Hypertension usually coexists with diabetes mellitus and significantly increases the risk of macrovascular complications. Blood pressure measured at home, especially nocturnal blood pressure, is particularly important because it is more strongly associated with target organ damage than clinical blood pressure measurements. Regular moderate aerobic exercise has been shown to have anti-hypertensive effects. This study aimed to investigate the effects of aerobic exercise on home blood pressure in patients with diabetes. This randomized crossover trial was based on outpatient treatment at a university hospital. In this randomized crossover trial, 124 patients with type 2 diabetes were randomly assigned to two groups over 56 days: an exercise preceding group (exercise intervention for 28 days and then no exercise intervention for the following 28 days) and an exercise lagging group (no exercise intervention for 28 days and then exercise intervention for the following 28 days). The associations between the nocturnal blood pressure and exercise intervention were assessed accordingly. A decrease in blood pressure was observed in the morning and evening, at 2 a.m. and 3 a.m. after exercise intervention; however, there was no significant difference between groups. Moderate exercise was not effective in lowering nocturnal blood pressure in this study.

【 授权许可】

Unknown