Green Synthesized Chitosan/Chitosan Nanoforms/Nanocomposites for Drug Delivery Applications

Polymers

Iyyakkannu Sivanesan¹  Selvaraj Mari²  Juhyun Shin³  Jaewook Oh³  Judy Gopal⁴  Manikandan Muthu⁴ 

[1] Department of Bioresources and Food Science, Konkuk University, Hwayang-dong, Gwangjin-gu, Seoul 05029, Korea;Department of Chemistry, Guru Nanak College, Chennai 600 042, India;Department of Stem Cell and Regenerative Biotechnology, Konkuk University, Seoul 143-701, Korea;Laboratory of Neo Natural Farming, Chunnampet, Tamil Nadu 603 401, India;

关键词: chitosan;    chitosan nanoparticles;    synthesis;    green synthesis;    drug delivery;   

DOI  :  10.3390/polym13142256

来源: DOAJ

【 摘 要 】

Chitosan has become a highlighted polymer, gaining paramount importance and research attention. The fact that this valuable polymer can be extracted from food industry-generated shell waste gives it immense value. Chitosan, owing to its biological and physicochemical properties, has become an attractive option for biomedical applications. This review briefly runs through the various methods involved in the preparation of chitosan and chitosan nanoforms. For the first time, we consolidate the available scattered reports on the various attempts towards greens synthesis of chitosan, chitosan nanomaterials, and chitosan nanocomposites. The drug delivery applications of chitosan and its nanoforms have been reviewed. This review points to the lack of systematic research in the area of green synthesis of chitosan. Researchers have been concentrating more on recovering chitosan from marine shell waste through chemical and synthetic processes that generate toxic wastes, rather than working on eco-friendly green processes—this is projected in this review. This review draws the attention of researchers to turn to novel and innovative green processes. More so, there are scarce reports on the application of green synthesized chitosan nanoforms and nanocomposites towards drug delivery applications. This is another area that deserves research focus. These have been speculated and highlighted as future perspectives in this review.

【 授权许可】

Unknown