Evaluating a novel behavioral paradigm for visual hallucinations in Dementia with Lewy bodies

Aging Brain

Glenda M. Halliday¹  Kaylena A. Ehgoetz Martens²  Elie Matar³  Joseph R. Phillips⁴  Ahmed A. Moustafa⁴  Simon J.G. Lewis⁴ 

[1] Dementia and Movement Disorders Laboratory, Brain and Mind Centre, University of Sydney, Sydney, New South Wales, Australia;Marcs Institute for Brain and Behaviour, Western Sydney University, Sydney, New South Wales, Australia;;School of Psychology &Faculty of Medicine and Health, Brain and Mind Centre and Central Clinical School, University of Sydney, Camperdown, Sydney, Australia;

关键词: Dementia with lewy bodies;    Visual hallucinations;    Misperceptions;   

DOI  :  

来源: DOAJ

【 摘 要 】

The aim of this study was to evaluate the utility of the Bistable Percept Paradigm (BPP), a computerised behavioural task that has previously been utilised for the assessment of visual hallucinations in Parkinson’s Disease, in a Dementia with Lewy bodies (DLB) cohort. Dementia with Lewy bodies patients demonstrated poorer performance than healthy controls (HC) on the BPP with significantly more misperceptions and a greater failure to detect bistable percepts correctly compared to HC. Further, the number of misperceptions was also correlated with the severity of hallucinations. The findings from this study demonstrate that the BPP is a viable tool to measure misperceptions in DLB patients.

【 授权许可】

Unknown