Succinate dehydrogenase deficient renal cell carcinoma: A case report

Urology Case Reports

Vimal Mittal¹  Hiroko Miyagi²  Raj A. Kumar³  Udaya Kumar⁴  Paul Crispen⁵ 

[1] Corresponding author. Research Assistant Urology Institute, University of Southern California, USA.;Joseph Aresty Department of Urology, Keck Medicine of USC, University of Southern California, Los Angeles, CA, USA;;Catherine &Citrus Memorial Hospital, Inverness, FL, USA;Department of Urology, University of Florida College of Medicine, University of Florida, Gainesville, FL, USA;

关键词: Renal cancer;    Renal cell carcinoma;    Succinate dehydrogenase;    Partial nephrectomy;   

DOI  :  

来源: DOAJ

【 摘 要 】

Succinate dehydrogenase (SDH) deficient renal cell carcinoma (RCC) are uncommon renal tumors that typically present in relatively younger patients. SDH mutations are known to cause cancer, but often presents with hereditary paragangliomas, pheochromocytomas, and gastrointestinal stromal tumors. This report details a case of SDH deficient RCC in a patient with no know contributing family history. Patient presented with recurrent urinary tract infections and groin pain. Computerized tomography (CT) revealed a 4 cm mass in the right kidney. Partial nephrectomy was performed, and the patient had an uneventful recovery. Immunohistochemical staining revealed the tumor was SDH negative.

【 授权许可】

Unknown