Clinical efficacy of toothpaste containing 8.0% arginine and calcium carbonate for teeth hypersensitivity

Journal of Dental Sciences

Yu-Chao Chang¹  Hui-Chieh Hsu¹  Shiuan-Shinn Lee² 

[1] Department of Dentistry, Chung Shan Medical University Hospital, Taichung, Taiwan;School of Public Health, Chung Shan Medical University, Taichung, Taiwan;

关键词: arginine;    calcium carbonate;    dentin hypersensitivity;    toothpaste;   

DOI  :  10.1016/j.jds.2013.06.008

来源: DOAJ

【 摘 要 】

The prevalence of dentin hypersensitivity in Taiwan has been reported up to 38%. The aim of this study was to evaluate the clinical efficacy of desensitizing toothpaste containing 8.0% arginine and calcium carbonate in treating dentin hypersensitivity. Forty-three participants with established two hypersensitive teeth were enrolled with informed consent. Air blast sensitivity assessments were conducted at baseline and again after four and eight weeks of twice-daily product use. The use of desensitizing toothpaste was found to significantly reduce dentin hypersensitivity (P < 0.001). The one-way analysis of variance analysis followed by Tukey's test indicated that this desensitizing toothpaste had a time-to-improvement distribution (P < 0.05). Taken together, the toothpaste containing 8.0% arginine and calcium carbonate provides a significant reduction in dentin hypersensitivity.

【 授权许可】

Unknown