A Comprehensive Review of Detection Methods for SARS-CoV-2

Microorganisms

Magali Cucchiarini¹  Mahdieh Alipour²  SolmazMaleki Dizaj²  Simin Sharifi²  Rovshan Khalilov³  Mohammad Samiei⁴  Irada Huseynova⁵  Elham Ahmadian⁶  MohammadReza Ardalan⁶  Sepide Zununi Vahed⁶  Aziz Eftekhari⁷  Leila Chodari⁸ 

[1] Center of Experimental Orthopaedics, Saarland University Medical Center, D-66421 Homburg/Saar, Germany;Dental and Periodontal Research Center, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz 5166-15731, Iran;Department of Biophysics and Biochemistry, Baku State University, Baku AZ 1148, Azerbaijan;Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz 5166-15731, Iran;Institute of Molecular Biology & Biotechnologies, Azerbaijan National Academy of Sciences, 11 Izzat Nabiyev, Baku AZ 1073, Azerbaijan;Kidney Research Center, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz 5166-15731, Iran;Pharmacology and Toxicology Department, Maragheh University of Medical Sciences, Maragheh 78151-55158, Iran;Physiology Department, Faculty of Medicine, Urmia University of Medical Sciences, Urmia 571478334, Iran;

关键词: COVID-19;    coronavirus;    detection;    epidemic;    nanotechnology;   

DOI  :  10.3390/microorganisms9020232

来源: DOAJ

【 摘 要 】

Recently, the outbreak of the coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, in China and its subsequent spread across the world has caused numerous infections and deaths and disrupted normal social activity. Presently, various techniques are used for the diagnosis of SARS-CoV-2 infection, with various advantages and weaknesses to each. In this paper, we summarize promising methods, such as reverse transcription-polymerase chain reaction (RT-PCR), serological testing, point-of-care testing, smartphone surveillance of infectious diseases, nanotechnology-based approaches, biosensors, amplicon-based metagenomic sequencing, smartphone, and wastewater-based epidemiology (WBE) that can also be utilized for the detection of SARS-CoV-2. In addition, we discuss principles, advantages, and disadvantages of these detection methods, and highlight the potential methods for the development of additional techniques and products for early and fast detection of SARS-CoV-2.

【 授权许可】

Unknown