Imatinib in PDGFR positive malignant solitary fibroustumour of the pleura

International Journal of Cancer Therapy and Oncology

Sarah Bigeni¹  Cynthia Jones¹  Joseph Galea² 

[1]Department of Acute Medicine, Mater Dei Hospital, Msida

[2]Department of Cardiothoracic Surgery, Mater Dei Hospital, Msida

关键词: Malignant Solitary Fibrous Tumours, Imatinib, Pleura, PDGFR;   

DOI  :  10.14319/ijcto.41.16

来源: DOAJ

【 摘 要 】

In 2013, two cases of malignant solitary fibrous tumours (MSFTs) were diagnosed in Malta. Both were inoperable at presentation. Both tumours expressed platelet-derived growth factor receptor (PDGFR) with no mutations and the tyrosine kinase inhibitor imatinib was prescribed. Nonetheless, treatment was not as effective as documented in previous case-reports.

【 授权许可】

Unknown