Preliminary Investigation on Degradation Behavior and Cytocompatibility of Ca-P-Sr Coated Pure Zinc

Coatings

Mingfeng Ke¹  Shenghui Su¹  Danhua Xie²  Qiangqiang Tang³ 

[1] Department of Orthopedics, Ningde Municipal Hospital of Ningde Normal University, Ningde 352100, China;Fujian Provincial Key Laboratory of Featured Materials in Biochemical Industry, College of Chemistry and Materials, Ningde Normal University, Ningde 352100, China;School of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, China;

关键词: coating;    zinc;    degradation behavior;    cytocompatibility;   

DOI  :  10.3390/coatings12010043

来源: DOAJ

【 摘 要 】

Zinc and its alloys show a good application prospect as a new biodegradable material. However, one of the drawbacks is that Zn and its alloys would induce the release of more Zn ions, which are reported to be cytotoxic to cells. In this study, a Ca-P-Sr bioactive coating was prepared on the surface of pure zinc by the hydrothermal method to address this issue. The morphology, thickness, and composition were characterized, and the effects of the coating on the degradation, cell viability, and ALP staining were investigated. The results demonstrated that the degradation rate of pure zinc was reduced, while the cytocompatibility was significantly improved after pure zinc was treated with Ca-P-Sr coating. It is considered that the Ca-P-Sr bioactive coating prepared by the hydrothermal method has promising application in the clinic.

【 授权许可】

Unknown