Seroprevalence of Hepatitis E Virus Infection among Blood Donors in Bulgaria

Viruses

Rumen Popov¹  Elisaveta Grancharova¹  Krasimira Terzieva¹  Magdalena Baymakova²  Roman Pepovich³  Ilia Tsachev⁴  Todor Kundurzhiev⁵ 

[1] Center of Transfusion Hematology, Military Medical Academy, 1606 Sofia, Bulgaria;Department of Infectious Diseases, Military Medical Academy, 1606 Sofia, Bulgaria;Department of Infectious Pathology, Hygiene, Technology and Control of Foods from Animal Origin, Faculty of Veterinary Medicine, University of Forestry, 1797 Sofia, Bulgaria;Department of Microbiology, Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, Trakia University, 6000 Stara Zagora, Bulgaria;Department of Occupational Medicine, Faculty of Public Health, Medical University, 1527 Sofia, Bulgaria;

关键词: hepatitis E virus;    blood donors;    seroprevalence;    Bulgaria;   

DOI  :  10.3390/v13030492

来源: DOAJ

【 摘 要 】

Hepatitis E virus (HEV) infection is widespread among domestic pigs, industrial swine, and wild boars in Bulgaria. The aim of the current research was to present the HEV seroprevalence among blood donors in Bulgaria. In the present study, 555 blood donors (479 males and 76 females) were enrolled from five districts in the country (Shumen, Pleven, Stara Zagora, Plovdiv, and Sofia districts). All blood samples were tested for anti-HEV IgG using the recomWell HEV IgG ELISA test (Mikrogen GmbH, Neuried, Germany). Each participating donor completed a short, structured, and specific questionnaire to document data on the current study. Anti-HEV IgG positive results were detected in 144 (25.9%) blood donors, including 129 (26.9%) males and 15 (19.7%) females. The established HEV seropositivity was 28.8% (23/80) in Shumen district, 23.2% (22/95) in Pleven district, 27.1% (38/140) in Stara Zagora district, 27.5% (44/160) in Plovdiv district, and 21.3% (17/80) in Sofia district. A high HEV seroprevalence was found for persons who declared that they were general hunters (48.7%; 19/39; p = 0.001) and hunters of wild boars (51.6%; 16/31; p = 0.001). We present the first seroprevalence rates of HEV infection in blood donors from Bulgaria. The results of our research showed high HEV seropositivity among blood donors.

【 授权许可】

Unknown