Biomaterials as Haemostatic Agents in Cardiovascular Surgery: Review of Current Situation and Future Trends

Polymers

Horațiu Moldovan¹  Silvia Preda¹  Maria Sabina Safta¹  Alexandru Scafa-Udrişte¹  Marian Broască¹  Mihai Cacoveanu¹  Daniela Gheorghiță²  Iulian Antoniac²  Oana Fronea³  Elisabeta Badilă³  Ondin Zaharia³  Adrian Molnar⁴  Victor Sebastian Costache⁵ 

[1] Department of Cardiovascular Surgery, Bucharest Clinical Emergency Hospital, 014461 Bucharest, Romania;Faculty of Materials Science and Engineering, Politehnica University of Bucharest, 060042 Bucharest, Romania;Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania;Faculty of Medicine, Iuliu Hateganu University of Medicine and Pharmacy, 400000 Cluj-Napoca, Romania;Sf. Constantin Hospital, 500388 Brasov, Romania;

关键词: haemostasis;    cardiovascular surgery;    coagulation;    haemostatic agents;    biomaterials;   

DOI  :  10.3390/polym14061189

来源: DOAJ

【 摘 要 】

Intraoperative haemostasis is of paramount importance in the practice of cardiovascular surgery. Over the past 70 years, topical haemostatic methods have advanced significantly and today we deal with various haemostatic agents with different properties and different mechanisms of action. The particularity of coagulation mechanisms after extracorporeal circulation, has encouraged the introduction of new types of topic agents to achieve haemostasis, where conventional methods prove their limits. These products have an important role in cardiac, as well as in vascular, surgery, mainly in major vascular procedures, like aortic dissections and aortic aneurysms. This article presents those agents used for topical application and the mechanism of haemostasis and offers general recommendations for their use in the operating room.

【 授权许可】

Unknown