Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells

Endocrine Regulations

Maslak Hanna S.¹  Kozynkevych Halyna E.²  Hnatiuk Oksana S.³  Tsymbal Dariia O.³  Khita Olena O.³  Viletska Yulia M.³  Rundytska Olha V.³  Minchenko Dmytro O.³  Minchenko Oleksandr H.³ 

[1] Dnipropetrovsk State Medical Academy,Dnipro, Ukraine;National Bohomolets Medical University,Kyiv, Ukraine;Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine,Kyiv, Ukraine;

关键词: silencing hspb8;    mrna expression;    irs1;    homer3;    perp;    clo1;    myl9;    per2;    gadd45a;    u87 glioma cells;   

DOI  :  10.2478/enr-2020-0026

来源: DOAJ

【 摘 要 】

Objective. The aim of the present investigation was to study the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other functionally active proteins in U87 glioma cells under silencing of polyfunctional chaperone HSPB8 for evaluation of the possible significance of this protein in intergenic interactions.

【 授权许可】

Unknown