Transcranial direct current stimulation for promoting motor function in cerebral palsy: a review

Journal of NeuroEngineering and Rehabilitation

Tim Theologis¹  Rachel Buckingham¹  Heidi Johansen-Berg²  Melanie K. Fleming² 

[1] Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust;Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital;

关键词: Cerebral palsy;    Motor function;    Transcranial direct current stimulation;    Brain stimulation;    Upper limb;    Lower limb;   

DOI  :  10.1186/s12984-018-0476-6

来源: DOAJ

【 摘 要 】

Abstract Transcranial direct current stimulation (tDCS) has the potential to improve motor function in a range of neurological conditions, including Cerebral Palsy (CP). Although there have been many studies assessing tDCS in adult stroke, the literature regarding the efficacy of tDCS in CP is more limited. This review therefore focuses on the neurophysiological and clinical findings in children and adolescents with CP. Initial studies applying anodal tDCS to promote lower limb function are promising, with improvements in gait, mobility and balance reported. However, the results of upper limb studies are mixed and more research is needed. Studies investigating neurophysiological changes or predictors of response are also lacking. Large-scale longitudinal studies are needed for the lower limb to ascertain whether the initial pilot results translate into clinically meaningful improvements. Future studies of the upper limb should focus on determining the optimal stimulation parameters and consider tailoring stimulation to the individual based on the (re)organisation of their motor system.

【 授权许可】

Unknown