Vitamin A Status Improvement in Obesity: Findings and Perspectives Using Encapsulation Techniques

Nutrients

Thais Souza Passos¹  Camila de Carvalho Gomes²  Ana Heloneida Araújo Morais² 

[1] Department of Nutrition, Health Sciences Center, Federal University of Rio Grande do Norte, Natal 59078 970, Brazil;Postgraduate Program in Biochemistry and Molecular Biology, Center for Biosciences, Federal University of Rio Grande do Norte, Natal 59078 970, Brazil;

关键词: retinoic acid;    adipose tissue;    provitamin A;    carotenoids;    solubility;    functionality;   

DOI  :  10.3390/nu13061921

来源: DOAJ

【 摘 要 】

The association between obesity and vitamin A has been studied. Some studies point to the anti-obesity activity related to this vitamin, carotenoids with provitamin A activity, and carotenoid conversion products. This performance has been evaluated in respect of adipogenesis, metabolic activity, oxidation processes, secretory function, and oxidative stress modulation, showing a new property attributed to vitamin A in preventing and treating obesity. However, vitamin A and its precursors are highly sensitive and easily degraded when subjected to heat, the presence of light, and oxygen, in addition to losses related to the processes of digestion and absorption. In this context, encapsulation presents itself as an alternative capable of increasing vitamin A’s stability in the face of unfavorable conditions in the environment, which can reduce its functionality. Considering that vitamin A’s status shows a strong correlation with obesity and is an innovative theme, this article addresses the associations between vitamin A’s consumption and its precursors, encapsulated or not, and its physiological effects on obesity. The present narrative review points out those recent studies that demonstrate that vitamin A and its encapsulated precursors have the most preserved functionality, which guarantees better effects on obesity therapy.

【 授权许可】

Unknown