Feasibility of Extracting Meaningful Patient Centered Outcomes From the Electronic Health Record Following Critical Illness in the Elderly

Frontiers in Medicine

Brenda Anderson¹  Luann Budahn¹  Kirtivardhan Vashistha²  Alex D. Tarabochia³  Allison M. Lemahieu⁴  Sumera R. Ahmad⁵  Lioudmila Karnatovskaia⁵  Ognjen Gajic⁵ 

[1] Anesthesia and Critical Care Research Unit, Mayo Clinic, Rochester, MN, United States;Department of Infectious Disease, Multi-disciplinary Epidemiology and Translational Research in Intensive Care Research Group, Mayo Clinic, Rochester, MN, United States;Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States;Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States;Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, United States;

关键词: critical illness;    trajectory;    patient important outcomes;    days alive and out of hospital/health care facility (DAOH);    electronic health records (EHR);   

DOI  :  10.3389/fmed.2022.826169

来源: DOAJ

【 摘 要 】

BackgroundMeaningful patient centered outcomes of critical illness such as functional status, cognition and mental health are studied using validated measurement tools that may often be impractical outside the research setting. The Electronic health record (EHR) contains a plethora of information pertaining to these domains. We sought to determine how feasible and reliable it is to assess meaningful patient centered outcomes from the EHR.MethodsTwo independent investigators reviewed EHR of a random sample of ICU patients looking at documented assessments of trajectory of functional status, cognition, and mental health. Cohen's kappa was used to measure agreement between 2 reviewers. Post ICU health in these domains 12 month after admission was compared to pre- ICU health in the 12 months prior to assess qualitatively whether a patient's condition was “better,” “unchanged” or “worse.” Days alive and out of hospital/health care facility was a secondary outcome.ResultsThirty six of the 41 randomly selected patients (88%) survived critical illness. EHR contained sufficient information to determine the difference in health status before and after critical illness in most survivors (86%). Decline in functional status (36%), cognition (11%), and mental health (11%) following ICU admission was observed compared to premorbid baseline. Agreement between reviewers was excellent (kappa ranging from 0.966 to 1). Eighteen patients (44%) remained home after discharge from hospital and rehabilitation during the 12- month follow up.ConclusionWe demonstrated the feasibility and reliability of assessing the trajectory of changes in functional status, cognition, and selected mental health outcomes from EHR of critically ill patients. If validated in a larger, representative sample, these outcomes could be used alongside survival in quality improvement studies and pragmatic clinical trials.

【 授权许可】

Unknown