Metabolic Syndrome—An Emerging Constellation of Risk Factors: Electrochemical Detection Strategies

Sensors

JayanthK. Babu¹  UmaMaheswari Krishnan¹  K.S. Shalini Devi²  JohnBosco Balaguru Rayappan²  Madhurantakam Sasya³ 

[1] Advanced Biomaterials (CeNTAB), SASTRA Deemed-to-be University, Thanjavur 613401, India;;Centre for Nanotechnology &Department of Molecular Physiology, School of Medicine, Niigata University, Niigata-9518510, Japan;

关键词: metabolic syndrome;    biomarkers;    biosensor;    electrochemistry;    nanomaterials;   

DOI  :  10.3390/s20010103

来源: DOAJ

【 摘 要 】

Metabolic syndrome is a condition that results from dysfunction of different metabolic pathways leading to increased risk of disorders such as hyperglycemia, atherosclerosis, cardiovascular diseases, cancer, neurodegenerative disorders etc. As this condition cannot be diagnosed based on a single marker, multiple markers need to be detected and quantified to assess the risk facing an individual of metabolic syndrome. In this context, chemical- and bio-sensors capable of detecting multiple analytes may provide an appropriate diagnostic strategy. Research in this field has resulted in the evolution of sensors from the first generation to a fourth generation of ‘smart’ sensors. A shift in the sensing paradigm involving the sensing element and transduction strategy has also resulted in remarkable advancements in biomedical diagnostics particularly in terms of higher sensitivity and selectivity towards analyte molecule and rapid response time. This review encapsulates the significant advancements reported so far in the field of sensors developed for biomarkers of metabolic syndrome.

【 授权许可】

Unknown