Chemical and morphological characterization of Allium tuncelianum (Amaryllidaceae) and its antioxidant and anticholinesterase potentials

Anales del Jardín Botánico de Madrid

Ozkan Aksakal¹  Haluk Caglar Kaymak²  Gulnur Eksi³  Mehmet Koca⁴  Betul Demirci⁵  Songul Karakaya⁶  Mehmet Emin Kaplan⁶ 

[1] Department of Biology, Faculty of Science, Ataturk University;Department of Horticulture, Faculty of Agriculture Ataturk University;Department of Pharmaceutical Botany, Faculty of Pharmacy, Ankara University;Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ataturk University;Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University;Department of Pharmacognosy, Faculty of Pharmacy, Ataturk University;

关键词: allium tuncelianum;    anticholinesterase;    endemic;    essential oil;    morphology;   

DOI  :  10.3989/ajbm.2523

来源: DOAJ

【 摘 要 】

Alzheimer’s disease is the main reason for dementia, which increases with age. Cholinesterase inhibition and antioxidant potentials of extracts and essential oils from bulbs of A. tuncelianum (Kollmann) Özhatay & al., an endemic species to Tunceli (easthern Turkey), were evaluated. The fraction extracted of ethyl acetate had the highest phenolics level, 1,1-diphenyl-2-picrylhydrazyl, and thiobarbituric acid antioxidant capacity. Also, the ethyl acetate fraction presented the highest acetylcholinesterase (15.98 ± 2.76%), and butyrylcholinesterase inhibition (47.33 ± 3.27%). Diallyl disulfide (49.8%), diallyl trisulfide (27.9%) and allyl methyl trisulfide (6.9%) were found to be the major components of essential oil. This paper shows that the ethyl acetate fraction of A. tuncelianum could be a potent source of antioxidant and anticholinesterase components.

【 授权许可】

Unknown