A New Customized Bioactive Glass Filler to Functionalize Resin Composites: Acid-Neutralizing Capability, Degree of Conversion, and Apatite Precipitation

Journal of Clinical Medicine

Tobias T. Tauböck¹  Thomas Attin¹  Matej Par¹  Zrinka Tarle² 

[1] Department of Conservative and Preventive Dentistry, Center for Dental Medicine, University of Zurich, 8032 Zurich, Switzerland;Department of Endodontics and Restorative Dentistry, School of Dental Medicine, University of Zagreb, 10000 Zagreb, Croatia;

关键词: dental resin composites;    fluoride-containing bioactive glass;    acid neutralization;    degree of conversion;    hydroxyapatite precipitation;   

DOI  :  10.3390/jcm9041173

来源: DOAJ

【 摘 要 】

This study introduced an experimental bioactive glass (BG) with a lower Na₂O content than conventional BG 45S5 (10.5 wt% vs. 24.5 wt%), additionally containing CaF₂ (12 wt%) and a network connectivity similar to that of BG 45S5. A series of experimental composites functionalized with 5–40 wt% of the novel BG was prepared and compared to a corresponding series of experimental composites functionalized with 5–40 wt% of BG 45S5. Commercial acidneutralizing materials (alkasite, giomer, and glass ionomer) were used as references. The capabilities of the materials to neutralize hydrochloric acid (pH = 2.6) and lactic acid (pH = 4.5) were evaluated by real-time pH measurements over 1 h. The degree of conversion and precipitation of calcium phosphate were also investigated. Data were analyzed using one-way and Welch ANOVA at an overall level of significance of 0.05. The acid-neutralizing potential of the experimental BG incorporated into resin composites was generally comparable to that of BG 45S5, and better than that of a giomer and glass ionomer. Fluorine was identified in the precipitate that developed on the composites functionalized with the experimental BG, suggesting a capability of forming fluorapatite. Unlike the 45S5 composition, the experimental BG did not impair the degree of conversion of resin composites. The novel BG filler is therefore an interesting candidate for future investigations of caries-preventive resin composites, and their potential clinical applicability for restorative, preventive, and orthodontic purposes.

【 授权许可】

Unknown