Methyl (2E)-3-[3-Benzyl-2-(3-methoxy-3-oxoprop-1-yn-1-yl)-2-(1-naphthyl)imidazolidin-1-yl]acrylate

Molbank

AlexandraS. Golubenkova¹  NikitaE. Golantsov¹  LeonidG. Voskressensky¹ 

[1] Organic Chemistry Department, Science Faculty, Peoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., 117198 Moscow, Russia;

关键词: propargylamine;    imidazolidine;    electron-deficient alkyne;   

DOI  :  10.3390/M1176

来源: DOAJ

【 摘 要 】

Compounds with propargylamine moiety are useful synthetic precursors of several important classes of nitrogen-containing heterocycles. The title compound, methyl (2E)-3-[3-benzyl-2-(3-methoxy-3-oxoprop-1-yn-1-yl)-2-(1-naphthyl)imidazolidine-1-yl]acrylate, has been prepared by domino-reaction, employing easily available 1-benzyl-2-(1-naphthyl)-4,5-dihydro-1H-imidazole and methyl propiolate in a high 92% yield. The structure of title compound was determined using ¹H-NMR, ¹³C-NMR, UV, FT-IR and HRMS (High-Resolution Mass Spectrometry).

【 授权许可】

Unknown