Laser Texturing as a Way of Influencing the Micromechanical and Biological Properties of the Poly(L-Lactide) Surface

Materials

Maria Szymonowicz¹  Magdalena Tomanik²  Jarosław Filipiak²  Magdalena Kobielarz²  Celina Pezowicz²  Agnieszka Rusak³  Katarzyna Mroczkowska⁴  Arkadiusz Antończak⁴ 

[1] Department of Experimental Surgery and Biomaterials Research, Faculty of Dentistry, Wroclaw Medical University, 50-326 Wrocław, Poland;Department of Mechanics, Materials and Biomedical Engineering, Wrocław University of Science and Technology, 50-370 Wrocław, Poland;Division of Histology and Embryology, Department of Human Morphology and Embryology, Faculty of Medicine, Wroclaw Medical University, 50-368 Wrocław, Poland;Laser and Fiber Electronics Group, Faculty of Electronics, Wroclaw University of Science and Technology, 50-372 Wrocław, Poland;

关键词: poly(L-lactide);    laser irradiation;    surface enhancement;    micromechanical properties;    cytotoxicity;   

DOI  :  10.3390/ma13173786

来源: DOAJ

【 摘 要 】

Laser-based technologies are extensively used for polymer surface patterning and/or texturing. Different micro- and nanostructures can be obtained thanks to a wide range of laser types and beam parameters. Cell behavior on various types of materials is an extensively investigated phenomenon in biomedical applications. Polymer topography such as height, diameter, and spacing of the patterning will cause different cell responses, which can also vary depending on the utilized cell types. Structurization can highly improve the biological performance of the material without any need for chemical modification. The aim of the study was to evaluate the effect of CO₂ laser irradiation of poly(L-lactide) (PLLA) thin films on the surface microhardness, roughness, wettability, and cytocompatibility. The conducted testing showed that CO₂ laser texturing of PLLA provides the ability to adjust the structural and physical properties of the PLLA surface to the requirements of the cells despite significant changes in the mechanical properties of the laser-treated surface polymer.

【 授权许可】

Unknown