Lipid Metabolism Profiles in Rheumatic Diseases

Frontiers in Pharmacology

Bin Zhou¹  Qi Wang²  Lihua Zhang³  Honglin Zhu⁶  Weilin Chen⁶ 

[1] Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China;Department of Radiology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China;Department of Rheumatology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China;Department of Rheumatology, Xiangya Hospital, Central South University, Changsha, China;National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China;Provincial Clinical Research Center for Rheumatic and Immunologic Diseases, Xiangya Hospital, Changsha, China;

关键词: dyslipidemia;    fatty acid metabolism;    rheumatic diseases;    lipid metablism;    statin;   

DOI  :  10.3389/fphar.2021.643520

来源: DOAJ

【 摘 要 】

Rheumatic diseases are a group of chronic autoimmune disorders that involve multiple organs or systems and have high mortality. The mechanisms of these diseases are still ill-defined, and targeted therapeutic strategies are still challenging for physicians. Recent research indicates that cell metabolism plays important roles in the pathogenesis of rheumatic diseases. In this review, we mainly focus on lipid metabolism profiles (dyslipidaemia, fatty acid metabolism) and mechanisms in rheumatic diseases and discuss potential clinical applications based on lipid metabolism profiles.

【 授权许可】

Unknown