Impact of Different Titanium Implant Thread Designs on Bone Healing: A Biomechanical and Histometric Study with an Animal Model

Journal of Clinical Medicine

Patricia Mazón¹  TiagoLuis Eliers Treichel²  JoseLuis Calvo-Guirado³  Jaime Aramburú Júnior⁴  SergioAlexandre Gehrke⁴  PiedadN. de Aza⁵  Letícia Pérez-Díaz⁶ 

[1] Departamento de Materiales, Óptica y Tecnologia Electrónica, Universidad Miguel Hernández, Avda. Universidad s/n, 03202 Elche (Alicante), Spain;Department of Anatomy, Faculty of Veterinary, Universidade de Rio Verde, 104, Rio Verde-GO 75901-970, Brazil;Department of Oral and Implant Surgery, Faculty of Health Sciences, Universidad Católica de Murcia (UCAM), 30107 Murcia, Spain;Department of Research, Biotecnos CP 11100-Montevideo, Uruguay;Instituto de Bioingenieria, Universidad Miguel Hernández, Avda. Ferrocarril s/n, 03202 Elche (Alicante), Spain;Laboratorio de Interacciones Molecular, Facultad de Ciencias, Universidad de la Republica, Calle Iguá 4225, 11400 Montevideo, Uruguay;

关键词: animal study;    dental implants;    implant design;    healing chamber;    thread design;   

DOI  :  10.3390/jcm8060777

来源: DOAJ

【 摘 要 】

Threads of dental implants with healing chamber configurations have become a target to improve osseointegration. This biomechanical and histometric study aimed to evaluate the influence of implant healing chamber configurations on the torque removal value (RTv), percentage of bone-to-implant contact (BIC%), bone fraction occupancy inside the thread area (BAFO%), and bone and osteocyte density (Ost) in the rabbit tibia after two months of healing. Titanium implants with three different thread configurations were evaluated: Group 1 (G1), with a conventional “v” thread-shaped implant design; Group 2 (G2), with square threads; and Group 3 (G3), the experimental group with longer threads (healing chamber). Ten rabbits (4.5 ± 0.5 kg) received three implants in each tibia (one per group), distributed in a randomized manner. After a period of two months, the tibia blocks (implants and the surrounding tissue) were removed and processed for ground sectioning to evaluate BIC%, BAFO%, and osteocyte density. The ANOVA one-way statistical test was used followed by the Bonferoni’s multiple comparison test to determine individual difference among groups, considering a statistical difference when p < 0.05. Histometric evaluation showed a higher BAFO% values and Ost density for G3 in comparison with the other two groups (G1 and G2), with p < 0.05. However, the RTv and BIC% parameters were not significantly different between groups (p > 0.05). The histological data suggest that the healing chambers in the implant macrogeometry can improve the bone reaction in comparison with the conventional thread design.

【 授权许可】

Unknown