Effects of Synthesis Conditions on the Formation of Si-Substituted Alpha Tricalcium Phosphates

International Journal of Molecular Sciences

Joanna Kolmas¹  Katarzyna Szurkowska¹  Łukasz Szeleszczuk² 

[1] Chair of Analytical Chemistry and Biomaterials, Department of Analytical Chemistry, Faculty of Pharmacy, Medical University of Warsaw, ul. Banacha 1, 02-097 Warsaw, Poland;Chair of Physical Pharmacy, Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Warsaw, ul. Banacha 1, 02-097 Warsaw, Poland;

关键词: α-TCP;    calcium phosphates;    bioceramics;    biomedical applications;    physico–chemical properties;   

DOI  :  10.3390/ijms21239164

来源: DOAJ

【 摘 要 】

Powders of α-TCP containing various amounts of silicon were synthesized by two different methods: Wet chemical precipitation and solid-state synthesis. The obtained powders were then physico–chemically studied using different methods: Scanning and transmission electron microscopy (TEM and SEM), energy-dispersive X-ray spectroscopy (EDS), powder X-ray diffractometry (PXRD), infrared and Raman spectroscopies (FT-IR and R), and solid-state nuclear magnetic resonance (ssNMR). The study showed that the method of synthesis affects the morphology of the obtained particles, the homogeneity of crystalline phase and the efficiency of Si substitution. Solid-state synthesis leads to particles with a low tendency to agglomerate compared to the precipitation method. However, the powders obtained by the solid-state method are less homogeneous and contain a significant amount of other crystalline phase, silicocarnotite (up to 7.33%). Moreover, the microcrystals from this method are more disordered. This might be caused by more efficient substitution of silicate ions: The silicon content of the samples obtained by the solid-state method is almost equal to the nominal values.

【 授权许可】

Unknown