EEG biomarkers of free recall

NeuroImage

M.J. Kahana¹  C. Keane²  B.S. Katerman²  J.K. Pazdera²  Y. Li² 

[1] Corresponding author.;University of Pennsylvania, United States;

关键词: Theta;    Gamma;    Alpha;    Retrieval;    Reinstatement;   

DOI  :  

来源: DOAJ

【 摘 要 】

Brain activity in the moments leading up to spontaneous verbal recall provide a window into the cognitive processes underlying memory retrieval. But these same recordings also subsume neural signals unrelated to mnemonic retrieval, such as response-related motor activity. Here we examined spectral EEG biomarkers of memory retrieval under an extreme manipulation of mnemonic demands: subjects either recalled items after a few seconds or after several days. This manipulation helped to isolate EEG components specifically related to long-term memory retrieval. In the moments immediately preceding recall we observed increased theta (4–8 Hz) power (+T), decreased alpha (8–20 Hz) power (-A), and increased gamma (40–128 Hz) power (+G), with this spectral pattern (+T-A + G) distinguishing the long-delay and immediate recall conditions. As subjects vocalized the same set of studied words in both conditions, we interpret the spectral +T-A + G as a biomarker of episodic memory retrieval.

【 授权许可】

Unknown