Rationale for Utilization of Hydrogel Rectal Spacers in Dose Escalated SBRT for the Treatment of Unfavorable Risk Prostate Cancer

Frontiers in Oncology

Olusola Obayomi-Davies¹  Siyuan Lei²  Michael Carrasquilla²  Simeng Suy²  Ryan A. Hankins²  Jonathan W. Lischalk³  Shaan Kataria⁴  Nima Aghdam⁵  Matthew Forsthoefel⁶  Michael C. Repka⁷  Brian T. Collins⁸  Sean P. Collins⁹  Jacqueline Lee^1,10  Michael Creswell^1,10 

[1] Reston Radiation Oncology, Arlington, VA, United States;Department of Radiation Medicine, MedStar Georgetown University Hospital, Washington, DC, United States;Department of Radiation Oncology at New York University (NYU) Long Island School of Medicine, Perlmutter Cancer Center at NYCyberKnife, New York, NY, United States;;Department of Radiation Oncology, Arlington &Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Boston, MA, United States;Department of Radiation Oncology, Radiotherapy Centers of Kentuckiana, Louisville, KY, United States;Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC, United States;Department of Radiation Oncology, Wellstar Kennestone Hospital, Marietta, GA, United States;Department of Urology, MedStar Georgetown University Hospital, Washington, DC, United States;Georgetown University School of Medicine, Washington, DC, United States;

关键词: prostate;    hydrogel;    rectal spacer;    radiotherapy;    radiation therapy;    SBRT;   

DOI  :  10.3389/fonc.2022.860848

来源: DOAJ

【 摘 要 】

In this review we outline the current evidence for the use of hydrogel rectal spacers in the treatment paradigm for prostate cancer with external beam radiation therapy. We review their development, summarize clinical evidence, risk of adverse events, best practices for placement, treatment planning considerations and finally we outline a framework and rationale for the utilization of rectal spacers when treating unfavorable risk prostate cancer with dose escalated Stereotactic Body Radiation Therapy (SBRT).

【 授权许可】

Unknown