Highly selective transition-metal-free transamidation of amides and amidation of esters at room temperature

Nature Communications

Guangchen Li¹  Michal Szostak¹ 

[1]Department of Chemistry, Rutgers University

DOI  :  10.1038/s41467-018-06623-1

来源: DOAJ

【 摘 要 】

Transamidation reactions usually require transition metal catalysts and/or harsh conditions. Here, the authors show a general and operationally-simple protocol for the transamidation of amides and amidation of esters by highly selective acyl cleavage with non-nucleophilic amines under mild conditions.

【 授权许可】

Unknown