Early instauration granulomatous pneumonitis associated with use of etanercept in seronegative spondyloarthropathy: Case report

Respiratory Medicine Case Reports

Germán Puerta¹  María B. Iriarte²  Carlos A. Cañas²  Liliana Fernández-Trujillo³  Luz F. Sua⁴  Eliana I. Morales⁵ 

[1] Corresponding author. Department of Internal Medicine, Pulmonology Service, Interventional Pulmonology, Avenida Simón Bolívar, Cra 98 No. 18-49, Fundación Valle del Lili, Tower 6, 4th Floor, Office 446, 760032, Cali, Colombia.;Faculty of Health Sciences, Universidad Icesi. Cali, Colombia;Department of Internal Medicine, Pulmonology Service, Interventional Pulmonology, Fundación Valle del Lili, Cali, Colombia;Department of Internal Medicine, Rheumatology Service, Fundación Valle del Lili, Cali, Colombia;Faculty of Health Sciences, Universidad Icesi. Cali, Colombia;

关键词: Etanercept;    Pulmonary granulomatosis;    TNF-α;    Anti-TNF;    Spondyloarthropathy;    Case report;   

DOI  :  

来源: DOAJ

【 摘 要 】

Spondyloarthropathies are a group of chronic inflammatory disorders that involve the joints of the axial skeleton, peripheral joints and have extra-articular manifestations. Treatment includes inhibitors of tumor necrosis factor α. Currently there are five approved inhibitors: a soluble receptor, Etanercept and four monoclonal.Etanercept has very low toxicity with pulmonary adverse reactions being very rare. We present the case of a patient who developed respiratory symptoms and pulmonary infiltrates of rapid evolution after the third dose of treatment with Etanercept.

【 授权许可】

Unknown