Association between comorbidity and health-related quality of life in a hypertensive population: a hospital-based study in Bangladesh

BMC Public Health

Afrin Sultana Chowdhury¹  Mohammed Akram Hossain²  Farhana Akter³  Adnan Mannan⁴  Abul Faisal Md. Nuruddin Chowdhury⁵  Parijat Biswas⁵  Susmita Dey Pinky⁵  Kazi Mahmuda Akter⁶  Md. Mashud Rana⁷  Nazmul Alam⁸  Naim Uddin Hasan A Chy⁹ 

[1] Department of Biotechnology and Genetic Engineering, Noakhali Science and Technology University;Department of Cardiology, 250 Bedded General Hospital;Department of Endocrinology, Chittagong Medical College;Department of Genetic Engineering & Biotechnology, Faculty of Biological Sciences, University of Chittagong;Department of Medicine, Chittagong Medical College;Department of Obstetrics and Gynaecology, Sir Salimullah Medical College Mitford Hospital;Department of Pharmacology and Therapeutics, Chittagong Medical College;Department of Public Health, Asian University for Women;Health Economics Research Group, Department of Economics, University of Chittagong;

关键词: Bangladesh;    Hypertension (HTN);    Health-Related Quality of Life (HRQoL);    EQ-5D-3L;    Comorbidity;   

DOI  :  10.1186/s12889-022-12562-w

来源: DOAJ

【 摘 要 】

Abstract Background Hypertension is a known risk factor for several chronic conditions including diabetes and cardiovascular diseases. However, little is known about its impact on Health-related quality of life (HRQoL) in the context of Bangladesh. This study aimed to evaluate the association of hypertension on HRQoL among Bangladeshi patients corresponding to the socio-demographic condition, comorbid conditions, treatment, and health outcomes. Methods A hospital based cross-sectional study was conducted using a pre-tested structured questionnaire among patients with hypertension in 22 tertiary medical college hospitals in Bangladesh. The study recruited male and female hypertensive patients of age ≥18 years between July 2020 to February 2021 using consecutive sampling methods. Health related quality of life was measured using the widely-used index of EQ-5D that considers 243 different health-related attributes and uses a scale in which 0 indicates a health state equivalent to death and 1 indicates perfect health status. The five dimensions of the quality index included mobility, self-care, usual activities, pain or discomfort, and anxiety or depression. Ordered logit regression and linear regression models were used to estimate the predictors of comorbidity and HRQoL. Results Of the 1,912 hypertensive patients, 56.2% were female, 86.5% were married, 70.7% were either overweight or obese, 67.6% had a family history of hypertension, and 85.5% were on anti-hypertensive medication. Among the individuals with comorbidities, 47.6% had diabetes, 32.3% were obese, 16.2% had heart disease, 15% were visually impaired, and 13.8% were suffering from psychological diseases. HRQoL was found to be inversely proportional to the number of comorbidities. The most frequent comorbidities of diabetes and obesity showed the highest EQ- 5D mean utilities of 0.59 and 0.64, respectively. Conclusions Prevalent comorbidities, diabetes and obesity were found to be the significant underlying causes of declining HRQoL. It is recommended that the comorbidities should be adequately addressed for better HRQoL. Special attention should be given to address mental health issues of patients with hypertension.

【 授权许可】

Unknown