Advances in understanding and managing atopic dermatitis [version 1; referees: 2 approved]

F1000Research

Robert Sidbury¹  Michael Barton² 

[1] Department of Pediatric Dermatology, Seattle Children’s Hospital, Seattle, WA, 98105, USA;University of Washington School of Medicine, Seattle, WA, 98195, USA;

关键词: Allergy & Hypersensitivity;    Atopic Dermatitis & Other Forms of Eczema;    Cellular Microbiology & Pathogenesis;    Dermatologic Pharmacology;    Innate Immunity;    Medical Genetics;    Medical Microbiology;    Musculoskeletal Pharmacology;    Pediatric Skin Diseases (incl. Genetic Diseases);   

DOI  :  10.12688/f1000research.6972.1

来源: DOAJ

【 摘 要 】

Atopic dermatitis is a chronic, pruritic skin disease characterized by an improperly functioning skin barrier and immune dysregulation. We review proposed atopic dermatitis pathomechanisms, emphasizing how these impact current perspectives on natural history, role of allergic sensitization, and future therapeutic targets.

【 授权许可】

Unknown