An Efficient Protocol for the Solid-phase Synthesis of Malondiamides

Molecules

关键词: Combinatorial chemistry – Solid-phase synthesis – Amides – Acylations – Peptides.;   

DOI  :  10.3390/10121438

来源: DOAJ

【 摘 要 】

A novel and straightforward solid-phase synthesis of malondiamides containing a free nitrogen has been developed. These intermediates, which can be directly obtained in good yield and purity, can be further derivatised. This approach can be used for the synthesis of large split-and-mix-libraries.

【 授权许可】

Unknown