The ins and outs of telomere crisis in cancer

Genome Medicine

John Maciejowski¹  Patrick von Morgen¹ 

[1]Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center

DOI  :  10.1186/s13073-018-0596-4

来源: DOAJ

【 摘 要 】

Editorial summary Telomere crisis is linked with many of the genomic alterations found in cancer genomes. A new understanding of how these alterations arise points towards an active role for innate immune sensors during crisis and to new opportunities for the treatment and diagnosis of cancer.

【 授权许可】

Unknown