期刊论文详细信息
Nanomaterials
Bacteriophage Based Biosensors: Trends, Outcomes and Challenges
Mazaher Gholipourmalekabadi1  LauraMaria De Plano2  Ali Hashemi3  Zahra Aliakbar Ahovan3  Alexander Seifalian4 
[1] Cellular and Molecular Research Centre, Iran University of Medical Sciences,Tehran 1449614535, Iran;Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98166 Messina, Italy;Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences,Tehran 1985717443, Iran;;Nanotechnology &
关键词: bacteriophage;    biosensors;    nanomaterials;    foodborne pathogens;    bacteria;    smart materials;    nanotechnology;    nanoparticles;    coronavirus;   
DOI  :  10.3390/nano10030501
来源: DOAJ
【 摘 要 】

Foodborne pathogens are one of the main concerns in public health, which can have a serious impact on community health and health care systems. Contamination of foods by bacterial pathogens (such as Staphylococcus aureus, Streptococci, Legionella pneumophila, Escherichia coli, Campylobacter jejuni and Salmonella typhimurium) results in human infection. A typical example is the current issue with Coronavirus, which has the potential for foodborne transmission and ruling out such concerns is often difficult. Although, the possible dissemination of such viruses via the food chain has been raised. Standard bacterial detection methods require several hours or even days to obtain the results, and the delay may result in food poisoning to eventuate. Conventional biochemical and microbiological tests are expensive, complex, time-consuming and not always reliable. Therefore, there are urgent demands to develop simple, cheap, quick, sensitive, specific and reliable tests for the detection of these pathogens in foods. Recent advances in smart materials, nanomaterials and biomolecular modeling have been a quantum leap in the development of biosensors in overcoming the limitations of a conventional standard laboratory assay. This research aimed to critically review bacteriophage-based biosensors, used for the detection of foodborne pathogens, as well as their trends, outcomes and challenges are discussed. The future perspective in the use of simple and cheap biosensors is in the development of lab-on-chips, and its availability in every household to test the quality of their food.

【 授权许可】

Unknown   

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