Synthesis, Properties, and Biodegradation of Sequential Poly(Ester Amide)s Containing γ-Aminobutyric Acid

International Journal of Molecular Sciences

Naoko Yamano¹  Norioki Kawasaki¹  Atsuyoshi Nakayama¹  Kazumasa Watanabe²  Ryo Tanaka²  Yuushou Nakayama²  Takeshi Shiono² 

[1] Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan;Department of Applied Chemistry, Graduate School of Engineering, Hiroshima University, 1-4-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8527, Japan;

关键词: poly(ester amide)s;    γ-aminobutyric acid;    thermal properties;    biodegradation;    seawater;    activated sludge;   

DOI  :  10.3390/ijms21103674

来源: DOAJ

【 摘 要 】

Poly(ester amide)s are attracting attention because they potentially have excellent thermal and mechanical properties as well as biodegradability. In this study, we synthesized a series of novel poly(ester amide)s by introducing γ-aminobutyric acid (GABA) regularly into polyesters, and investigated their properties and biodegradabilities. GABA is the monomer unit of biodegradable polyamide 4 (PA4). The new poly(ester amide)s were synthesized from the reaction of ammonium tosylate derivatives of alkylene bis(γ-aminobutylate) and p-nitrophenyl esters of dicarboxylic acids. All the obtained polymers showed relatively high melting temperatures (T_m). Their thermal decomposition temperatures were improved in comparison with that of PA4 and higher enough than their T_m. The poly(ester amide)s exhibited higher biodegradability in seawater than the corresponding homopolyesters. Their biodegradabilities in activated sludge were also studied.

【 授权许可】

Unknown