Efficacy of a Modified Clinoptilolite Based Adsorbent in Reducing Detrimental Effects of Ochratoxin A in Laying Hens

Toxins

Jelka Pleadin¹  Branko Petrujkić²  Jelena Nedejković Trialović²  Darko Marinković³  Saša Trialović⁴  Srđan Stefanović⁵  Dragan Milićević⁵  Jog Raj⁶  Marko Vasiljević⁷ 

[1] Croatian Veterinary Institute, Laboratory for Analytical Chemistry, Savska cesta 143, 10000 Zagreb, Croatia;Department of Animal Nutrition and Botany, Faculty of Veterinary Medicine, University of Belgrade, Bulevar oslobodjenja 18, 11000 Belgrade, Serbia;Department of Pathology, Faculty of Veterinary Medicine, University of Belgrade, Bulevar oslobodjenja 18, 11000 Belgrade, Serbia;Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Belgrade, Bulevar oslobodjenja 18, 11000 Belgrade, Serbia;Institute of Meat Hygiene and Technology, Kaćanskog 13, 11040 Belgrade, Serbia;Patent Co, DOO., Vlade Ćetkovića 1A, 24211 Mišićevo, Serbia;The Faculty of Veterinary Medicine, University of Belgrade, Bulevar oslobodjenja 18, 11000 Belgrade, Serbia;

关键词: adsorbent;    OTA;    performance traits;    pathohistological changes;    OTA residue;    eggs;   

DOI  :  10.3390/toxins13070469

来源: DOAJ

【 摘 要 】

Background: The objective of this study was to evaluate the efficacy of modified clinoptilolite (Minazel Plus^®, MZ) as a mycotoxin adsorbent for preventing the negative the effects of ochratoxin A (OTA) on performance, pathohistological changes, and OTA residue in the eggs of laying hens. Methods: Forty eight (n = 48) laying hens (27 weeks old) were equally divided into six groups and depending on the type of addition were allocated to the following experimental treatments for 7 weeks: E-I group-1 mg/kg OTA; E-II group 0.25 mg/kg OTA; E-III group 1 mg/kg OTA + 0.2% of MZ; E-IV group 0.25 mg/kg OTA + 0.2% of MZ; MZ group supplemented with 0.2% of the adsorbent; and control (K, without feed additive). Results: Overall, the addition of 0.2% MZ to laying hen feed mitigated the harmful effects of OTA on target organs and reduced the presence of OTA residue in eggs. The groups that received 0.2% of MZ achieved better production results in terms of body weight, number of eggs, and feed consumption, compared to the other treatments. Conclusions: The current findings confirm the efficacy of MZ in preventing performance losses in laying hens exposed to OTA, as well as for improving the welfare and health of food producing animals.

【 授权许可】

Unknown