Trial Direct Phasing Calculation of A Thyroid Hormone Receptor Alpha Structure (4LNW)

Crystals

Hongxing He¹  Mengchao Jiang¹  Wu-Pei Su¹ 

[1]Department of Physics and Texas Center for Superconductivity, University of Houston, Houston, TX 77204, USA

关键词: ab initio phasing;    iterative projection algorithm;    protein crystallography;   

DOI  :  10.3390/cryst9100533

来源: DOAJ

【 摘 要 】

A thyroid receptor alpha structure (PDB ID: 4LNW) was studied for ab initio phasing. With the diffraction intensity data, protein sequence, and ligand structure as the only input, a high-resolution structure was successfully reconstructed by using an iterative projective method based on the hybrid input−output (HIO) algorithm.

【 授权许可】

Unknown