One-Pot Synthesis of SiO2@Ag Mesoporous Nanoparticle Coating for Inhibition of Escherichia coli Bacteria on Various Surfaces

Nanomaterials

Kyoung Lee¹  DongSik Bae²  Sukhbayar Gankhuyag³  Seunghyun Lee³ 

[1] Department of Bio Health Science, Changwon National University, Changwon 51140, Gyeongsangnam-do, Korea;Department of Convergence Materials Science and Engineering, Changwon National University, Changwon 51140, Gyeongsangnam-do, Korea;Department of Electronic Engineering, Kyung Hee University, Yongin 17104, Gyeonggi-do, Korea;

关键词: silver nanoparticles;    Gram-negative vs. Gram-positive;    antibacterial agents;    impregnation method;    coating;   

DOI  :  10.3390/nano11020549

来源: DOAJ

【 摘 要 】

Silver nanoparticles (Ag NPs) as antibacterial agents are of considerable interest owing to their simplicity, high surface area to volume ratio, and efficient oligodynamic properties. Hence, we investigated the synthesis of silica-supported Ag NPs (SiO₂@Ag) as an effective antibacterial agent by using a wet-impregnation method. The formation of SiO₂@Ag with Ag NP (5–15 nm diameter) on the silica particle (100–130 nm diameter) was confirmed with transmission electron microscopy (TEM). The study on antibacterial activity was performed in a liquid culture to determine the minimum inhibitory concentration (MIC) against Escherichia coli (E. coli) and Bacillus subtilis (B. subtilis) bacteria. Both bacteria are chosen to understand difference in the effect of Ag NPs against Gram-negative (E. coli) and Gram-positive (B. subtilis) bacteria. SiO₂@Ag mesoporous nanoparticles had excellent antibacterial activity against E. coli bacteria and fully restricted the bacterial growth when the material concentration was increased up to 1.00 mg/mL. In addition, the obtained material had good adhesion to both steel and polyethylene substrates and exhibited a high inhibition effect against E. coli bacteria.

【 授权许可】

Unknown