Air leakage in seals with application to syringes

Applied Surface Science Advances

A. Tiwari¹  N. Rodriguez²  B.N.J. Persson³ 

[1] BD Medical-Pharmaceutical Systems, 1 Becton Drive, Franklin Lakes NJ 07417, USA;Corresponding author.;Peter Grünberg Institute (PGI-1), Forschungszentrum Jülich, 52425 Jülich, Germany;

关键词: Teflon coating;    Syringe leakage;    Ballistic gas flow;    Contact mechanics;    Elastoplasticity;    Viscoelasticity;   

DOI  :  

来源: DOAJ

【 摘 要 】

We study the leakage of air in syringes with Teflon coated rubber stopper and glass barrel. The leakrate depends on the interfacial surface roughness, the viscoelastic properties of the rubber and on the elastoplastic properties of the Teflon coating. The measured leakage rates are compared to the predictions of a simple theory for gas flow, which takes into account both the diffusive and ballistic air flow, and the elastoplastic multiscale contact mechanics which determines the probability distribution of interfacial separations. The theory shows that the interfacial air flow (leakage) channels are so narrow that the gas flow is mainly ballistic (the so called Knudsen limit). The implications for container closure integrity is discussed.

【 授权许可】

Unknown