Description of a neural sheath tumor of the trigeminal nerve: immunohistochemical and electron microscopy study

São Paulo Medical Journal

Seied Mohammad Owji¹  Mohammad Mohammadianpanah¹  Khadije Jamshidi Khosh¹  Bijan Khademi¹  Behrooz Gandomi¹ 

[1] Shiraz University of Medical Sciences;

关键词: Nerve sheath neoplasms;    Paranasal sinuses;    Trigeminal nerve;    Radiotherapy;    Chemotherapy;   

DOI  :  10.1590/S1516-31802006000600006

来源: DOAJ

【 摘 要 】

CONTEXT: Malignant neural sheath tumors of the trigeminal nerve affecting the nasal cavity and the paranasal sinuses are extremely rare. With conventional optical microscopy, their identification is difficult, and it is necessary to confirm them by means of electron microscopy and immunohistochemical techniques. CASE REPORT: The patient was a 41-year-old woman with a ten-month progressive history of pain followed by painful edema in the left facial region, and with symptoms of bleeding, secretion and nasal obstruction. Studies with imaging methods suggested the presence of an expansive process in the left nasal and paranasal cavities. In the biopsy, the histopathological findings from optical microscopy were suggestive of a tumor of neural origin in the trigeminal nerve. Immunohistochemical and electron microscopy studies confirmed that it was a malignant tumor of the neural sheath of the trigeminal nerve. We describe the clinical, radiological, and histological features of this tumor and review the literature.

【 授权许可】

Unknown