Sarcopenia and Liver Cirrhosis—Comparison of the European Working Group on Sarcopenia Criteria 2010 and 2019

Nutrients

Julia Traub¹  Vanessa Stadlbauer²  Martin Eibisberger³  Ina Bergheim⁴ 

[1] Department of Clinical Medical Nutrition, University Hospital Graz, 8036 Graz, Austria;Department of Internal Medicine Division of Gastroenterology und Hepatology Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria;Department of Neuroradiology, Vascular and Interventional Radiology, Medical University of Graz, 8036 Graz, Austria;Department of Nutritional Sciences, RF Molecular Nutritional Science, University Vienna, 1090 Vienna, Austria;

关键词: liver cirrhosis;    sarcopenia;    consensus;    muscle strength;   

DOI  :  10.3390/nu12020547

来源: DOAJ

【 摘 要 】

The European Working group on Sarcopenia in Older People recently updated the diagnostic criteria for sarcopenia. It is yet unclear how these modified criteria influence the rate of diagnosis in high risk populations, such as liver cirrhosis. We therefore assessed if the new diagnostic criteria for sarcopenia impacts on sarcopenia prevalence in liver cirrhosis. Within two years 114 cirrhotic patients were prospectively enrolled in the study. Sarcopenia was determined by muscle strength (handgrip strength), muscle mass (lumbal muscle index) and muscle performance (gait speed). Using the 2019 definition, the rate of pre-sarcopenia was significantly lower (30.7% versus 3.5%) due to the different starting points (2010 muscle mass, 2019 muscle strength) and cut-off values (muscle strength). The change in diagnostic criteria for sarcopenia drastically influences the rate of pre-sarcopenia diagnosis in cirrhotics. To evaluate, which diagnostic criteria should be chosen to diagnose sarcopenia in liver cirrhosis patients, prospective studies are needed.

【 授权许可】

Unknown