Optimal gestational weight gain for Chinese women - analysis from a longitudinal cohort with childhood follow-up

The Lancet Regional Health. Western Pacific

Wing Hung Tam, MD¹  Ronald Ching-Wan Ma, FRCP²  Claudia Ha-Ting Tam, PhD²  Lai Yuk Yuen, BSc³  Yuanying He, MM³  Patrick M. Catalano, MD⁴ 

[1] Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China;Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China;Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China;Maternal Infant Research Institute, Tufts University School of Medicine, Tufts Medical Center, Boston, MA, USA.;

关键词: Gestational weight gain (GWG);    Reference ranges;    Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study;    Longitudinal cohort;    Neonatal adiposity;    Birth weight;   

DOI  :  

来源: DOAJ

【 摘 要 】

Background: Maternal gestational weight gain (GWG) influences not only on pregnancy outcome but also impacts on mothers’ and children's long-term health. However, there is no consensus on recommendations of optimal GWG in Asians or the Chinese population. Methods: We performed a secondary analysis of the birth outcome of Chinese women who had joined the “Hyperglycemia and Adverse Pregnancy Outcome” study in Hong Kong and their children's cardiometabolic risk at 7-year of age. Optimal ranges of GWG were derived from models based on the probabilities of small for gestational age and large for gestational age (model 1), lean and fat infants (model 2) and the integration of model 1 and 2 (model 3), and were compared with that recommended by the Institute of Medicine (IOM) on children's cardiometabolic risk. Findings: GWG range derived from model 2 is associated with 8 cardiometabolic risk factors, while that from models 1 and 3 are associated with 1 and 7 of them respectively. Mothers whose GWG lie within the recommended range increases from 40.8% according to the IOM recommendation to 50.2% according to that derived from model 2. Interpretation: Optimal GWG derived from model 2 (i.e. 14.0-18.5 kg, 9.0-16.5 kg and 5.0-11.0 kg for underweight, normal weight and overweight Chinese women, respectively) appeared to be associated with the lowest cardiometabolic risk in the offspring. Funding: General Research Fund of the Research Grants Council of the Hong Kong SAR, China (grants CUHK 473408 and, in part, CUHK 471713).

【 授权许可】

Unknown