Medical image of the week: Pulmonary amyloidosis in primary Sjogren’s syndrome

Southwest Journal of Pulmonary and Critical Care

Chang B¹  Sen P¹ 

[1] University of New Mexico, Albuquerque, NM USA;

关键词: Sjögren;    Sjögren's;    nodules;    cysts;    amydoid. amyloidosis;    diffuse septal alveolar amyloidosis;    treatment;    diagnosis;    CT scan;    bortezomib;   

DOI  :  10.13175/swjpcc072-18

来源: DOAJ

【 摘 要 】

No abstract available. Article truncated after 150 words. A 69-year-old woman with past medical history of Sjögren's syndrome presented with pleuritic chest pain and shortness of breath for a month. Review of systems revealed worsening dysphagia and dryness of eyes over the last one year. Physical exam was significant for a palpable left axillary node and mild rhonchi bilaterally in the lower lung bases. Laboratory work was positive for Sjogren’s Syndrome antibodies. Chest x-ray revealed multiple nodules in bilateral lung fields. HRCT showed interlobular septal thickening and multiple cystic areas throughout the lung parenchyma which had progressed over 1 year (Figure 1). Wedge resection and thorough lymph node dissection were performed via video-assisted thoracic surgery (VATS). Biopsy of the lung nodules revealed thickened alveolar septate with acellular eosinophilic homogenous materials, which took up Congo Red stain. Based on these pathological findings, the final diagnosis was - diffuse septal alveolar pulmonary amyloidosis secondary to Sjogren’s Syndrome. bortezomib. However, the …

【 授权许可】

Unknown