The Role of Exosomes and Their Cargos in the Mechanism, Diagnosis, and Treatment of Atrial Fibrillation

Frontiers in Cardiovascular Medicine

Shengyuan Huang¹  Liming Liu¹  Chengming Fan¹  Jiaqi Xu²  Yating Deng³  Jiachen Liu³ 

[1]Department of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, China

[2]Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China

[3]Xiangya Medical College of Central South University, Changsha, China

关键词: non-coding RNA;    exosomes;    atrial fibrillation;    biomarkers;    mechanism;    treatment;   

DOI  :  10.3389/fcvm.2021.712828

来源: DOAJ

【 摘 要 】

Atrial fibrillation (AF) is the most common persistent arrhythmia, but the mechanism of AF has not been fully elucidated, and existing approaches to diagnosis and treatment face limitations. Recently, exosomes have attracted considerable interest in AF research due to their high stability, specificity and cell-targeting ability. The aim of this review is to summarize recent literature, analyze the advantages and limitations of exosomes, and to provide new ideas for their use in understanding the mechanism and improving the diagnosis and treatment of AF.

【 授权许可】

Unknown