Cerebrospinal Fluid Immunoglobulins as Potential Biomarkers of Chikungunya Encephalitis

Emerging Infectious Diseases

关键词: chikungunya virus;    CHIKV;    alphavirus;    humoral immune response;    cerebrospinal fluid;    meningitis/encephalitis;   

DOI  :  10.3201/eid2405.171763

来源: DOAJ

【 摘 要 】

Chikungunya virus causes fever and severe polyarthritis or arthralgia and is associated with neurologic manifestations that are sometimes challenging to diagnose. We demonstrate intrathecal synthesis of chikungunya antibodies in a patient with a history of acute infection complicated by encephalitis. The specificity of the intracerebral immune response supports early chikungunya-associated encephalitis diagnosis.

【 授权许可】

Unknown