Quality by Design: A Suitable Methodology in Industrial Pharmacy for Costa Rican Universities

Scientia Pharmaceutica

Lexi Chaves-Siles¹  Édgar Hernández-Mora¹  Brayan Murillo-Castillo²  Juan José Mora-Román²  Nils Ramírez-Arguedas²  Luis Castillo-Henríquez³  José Vega-Baudrit³ 

[1] Faculty of Pharmacy, Universidad Internacional de Las Américas (UIA), San José 1447-1002, Costa Rica;Faculty of Pharmacy, University of Costa Rica (UCR), San José 11501-2060, Costa Rica;National Laboratory of Nanotechnology (LANOTEC), National Center for High Technology (CeNAT), San José 1174-1200, Costa Rica;

关键词: academy;    formulation development;    industrial pharmacy;    manufacturing process;    pharmaceutical technology;    quality by design;   

DOI  :  10.3390/scipharm90020034

来源: DOAJ

【 摘 要 】

This review aims to present the Quality by Design (QbD) model as a suitable methodology to perform research in the academic Costa Rican institutions that teach Pharmacy. Pubmed, Science Direct, and Google Scholar databases were screened for original research papers and review papers published not more than ten years ago. Institutional repositories from the different universities were reviewed as well. The QbD model stands out as a great methodology for carrying out research projects regarding Pharmaceutical Sciences, but especially for Industrial Pharmacy, where it has contributed in terms of formulation development, manufacturing, and quality control. Academic research based on this model enables the training and development of practical, scientific, and leadership skills in Industrial Pharmacy students. The generated knowledge can be shared in classrooms, which represents an ideal environment to communicate research results and to foster collaborative work between researchers, professors, and students. Moreover, research performed through a QbD approach increases the confidence shown by the industrial sector and health regulatory authorities in the quality of the research, products, and knowledge that are developed and created in an Academy. As a result, the implementation of the model has allowed the creation, transfer, and materialization of knowledge from the Costa Rican Academy to different local pharmaceutical industries.

【 授权许可】

Unknown