Prenatal and postnatal evaluation of polymicrogyria with band heterotopia

Radiology Case Reports

Beth Kline-Fath, MD¹  Usha D. Nagaraj, MD¹  Mark Schapiro, MD²  Robert Hopkin, MD² 

[1] Department of Radiology and Medical Imaging, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3026, USA;University of Cincinnati College of Medicine, Cincinnati, OH, USA;

关键词: Fetal MRI;    Polymicrogyria;    Band heterotopia;   

DOI  :  10.1016/j.radcr.2017.04.007

来源: DOAJ

【 摘 要 】

The coexistence of band heterotopia and polymicrogyria is extremely rare though it has been reported in the presence of corpus callosum anomalies and megalencephaly. We present prenatal and postnatal MRI findings of a rare case of diffuse cortical malformation characterized by polymicrogyria and band heterotopia. Agenesis of the corpus callosum and megalencephaly were also noted. In addition, bilateral closed-lip schizencephaly was identified on postnatal MRI, which has not been previously reported with this combination of imaging findings. Polymicrogyria with band heterotopia can occur and can be diagnosed with fetal MRI. The coexistence of corpus callosum anomalies and megalencephaly comprises a rare phenotype that has been previously described, suggesting an underlying genetic abnormality.

【 授权许可】

Unknown