Metabolites | |
Increased Reliance on Carbohydrates for Aerobic Exercise in Highland Andean Leaf-Eared Mice, but Not in Highland Lima Leaf-Eared Mice | |
Marie-Pierre Schippers1  Grant B. McClelland1  Oswaldo Ramirez2  Margarita Arana2  | |
[1] Department of Biology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada;Unidad Biología Integrativa, Departamento de Ciencias Biológicas y Fisiológicas, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima 15102, Peru; | |
关键词: altitude; carbohydrates; respirometry; aerobic capacity; fuel use; muscle; | |
DOI : 10.3390/metabo11110750 | |
来源: DOAJ |
【 摘 要 】
Exercise is an important performance trait in mammals and variation in aerobic capacity and/or substrate allocation during submaximal exercise may be important for survival at high altitude. Comparisons between lowland and highland populations is a fruitful approach to understanding the mechanisms for altitude differences in exercise performance. However, it has only been applied in very few highland species. The leaf-eared mice (LEM, genus Phyllotis) of South America are a promising taxon to uncover the pervasiveness of hypoxia tolerance mechanisms. Here we use lowland and highland populations of Andean and Lima LEM (P. andium and P. limatus), acclimated to common laboratory conditions, to determine exercise-induced maximal oxygen consumption (
【 授权许可】
Unknown